# Introduction `katdetectr` is an *R* package for the detection, characterization and visualization of localized hypermutated regions, often referred to as *kataegis*. Please see the [Application Note](https://www.biorxiv.org/content/10.1101/2022.07.11.499364v1) (under submission) for additional background, details and performance evaluations of `katdetectr`. The general workflow of `katdetectr` can be summarized as follows: 1. Import of genomic variants; VCF, MAF or VRanges objects. 2. Detection of kataegis foci. 3. Visualization of segmentation and kataegis foci. Please see the [vignette](https://bioconductor.org/packages/release/bioc/vignettes/katdetectr/inst/doc/General_overview.html) for an overview of the workflow in a step-by-step manner on publicly-available datasets which are included within this package. ## Installation Download katdetectr from BioConductor: ```R if (!requireNamespace("BiocManager", quietly = TRUE)) install.packages("BiocManager") BiocManager::install("katdetectr") ```